Balkan Endemic Nephropathy Etiology...

03.03.2006, 15:21

BALKAN ENDEMIC NEPHROPATHY ETIOLOGY: A LINK BETWEEN GEOCHEMISTRY AND MEDICINE

Articol din publicatia Timisoara Medical Journal nr. 3/2005
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Authors: Erika I. Suciu[1], Valentin Ordodi[1], Diana N. Szilagyi[1], Calin A. Tatu[1], William H. Orem[2], Harry E. Lerch[2], Joseph Bunnell[2], Virgil Paunescu[1]

1 Department of Physiology and Immunology, Victor Babes University of Medicine and Pharmacy Timisoara, Romania
2 US Geological Survey, National Center MS 956, Reston VA 20192, USA

ABSTRACT
Balkan endemic nephropathy (BEN) is an irreversible, chronic, tubulo-interstitial nephropathy of unknown origin, geographically confined to several rural regions of the Balkan Peninsula. The geological setting of the endemic areas in the affected countries is similar. Most of the BEN villages are located on alluvial plains of tributaries of the Danube River, with older Tertiary layers (clays, sands and Pliocene lignites) covered by Quaternary river sediments. It is estimated that several thousand people in the affected countries are currently suffering from BEN and that thousands more will be diagnosed with BEN in the coming years.

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