3D Simulation of the Blood Flow in Arterial Stenosis
04.01.2006, 12:09
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Articol din publicatia Timisoara Medical Journal nr. 2/2005
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Sandor Ianos Bernad[1], Romeo Susan-Resiga[2], Elena Bernad[3], Dan Gaita[4]
1 Romanian Academy - Timisoara Branch
2 Polytechnical University, Department of Hydraulic Machinery, Timisoara
3 "Victor Babes" University of Medicine and Pharmacy, Timisoara, Institute of Cardiovascular Medicine
Correspondence to:
Sandor Ianos Bernard, Eng., PhD., Romanian Academy - Timisoara Branch
B-dul Mihai Viteazul 24, Timisoara, RO-300223, Romania
Tel: +40-256-403698, Fax: +40-256-403700
Email: sbernad@mh.mec.utt.ro
ABSTRACT
The basic features scrutinized during the analysis of the 3D flow in blood vessels are the flow separation and reattachment at the vessel wall where two stagnation points appear. An interesting aspect of the flow structure in a 3D stenosis model is the generation and propagation of a vortex, downstream of the constricted region. Specifically, the regions near the expansion wall and the reattachment point are susceptible to both atherosclerotic lesion and thrombi formations, as indicated by non-uniform hemodynamic indicators, such as near-zero wall shear stress and elevated wall shear stress gradients, as well as blood particle accumulation and deposition. Furthermore, disturbed flow regions, correlated with arterial wall dysfunctions, play an important role in the thrombosis generation.